pgy1pDr. Karen Ho is recruiting a postdoctoral scientist in her NIH-funded laboratory (https://sites.northwestern.edu/karenholab/). Applicant should have a background and interest in microbiology, particularly in the mammalian host-microbe interface. We have a unique and exciting research program in how gut microbes and microbe-derived metabolites alter immunological, metabolic and cellular pathways in atherosclerosis and arterial restenosis after vascular surgery, with the goal of discovering novel targets, biomarkers and therapies. The Ho laboratory is closely integrated with our clinical research. In our pursuit of “bench-to-bedside” integration, we use cellular and animal models (germ-free and conventional), flow cytometry, targeted metabolomics, and transcriptomic data analysis. We are seeking a highly motivated candidate to join the team studying the gut microbiome in vascular diseases. Primary Job Duties and Responsibilities: • Independently lead day to day operations of their own project. • Assist in preparation of grant proposals, but is not responsible for generating grant funds. • May participate in publications and presentations as author or co-author. • May develop, adapt, and implement new research techniques and protocols. • Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. • Analyzes, interprets, summarizes and compiles data. • Operates and maintains equipment and instruments. • Develop figures, searches scientific literature, assists in writing manuscripts, submits abstracts, and presents data at local and national meetings. • Handle and organize human clinical specimens. • Organize clinical samples. • May perform routine animal surgeries and procedures. • Perform standard microbiology and microbiome-based assays (cultivations, sequencing, in vitro assays, gnotobiotic mouse experiments). • Spearhead new tools and technologies and interact with collaborators and other research team members Minimum Qualifications: We seek highly motivated investigators with recent PhD or MD degree who are self-starters, strong communicators and independent problem solvers. Strong background in cellular immunology, molecular/cell biology, and computational skills required. Prefer a solid background in microbiology and experience leading research projects in this discipline and preferably with application to gut microbiomes. Prior experience with microbial cultivation and sequencing techniques is also preferred. Minimum Competencies: Applicants with experience in cellular/molecular biology, microbiology/microbiome, mouse experimentation, systems biology, and data science preferred. Candidates should have demonstrated ability to be highly motivated and organized, detail-oriented, and work independently. Candidates should have excellent command of the English language (spoken and written), and must be eligible to work in the US.